Actively Recruiting
Childhood B-acute Lymphoblastic Leukaemia and Role of CD9 Gene Regulation in Relapse
Led by Rennes University Hospital · Updated on 2026-01-02
50
Participants Needed
3
Research Sites
523 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
B-acute lymphoblastic leukaemia (B-ALL) is the most common cancer in children, with 20% of patients relapsing. CD9, a transmembrane protein, is linked to the migratory and adhesion capacities of leukaemia cells and could be associated with relapses. The aim of this project is to understand how CD9 regulation can be a marker of potential relapses, using bone and blood sampling of newly diagnosed patients at 3 crucial moments of therapy.
CONDITIONS
Official Title
Childhood B-acute Lymphoblastic Leukaemia and Role of CD9 Gene Regulation in Relapse
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Under 18 years
- Established diagnosis of B-acute lymphoblastic leukaemia (B-ALL)
- Initial diagnosis made at the investigating centre
- Received oral and written information about the protocol, or oral only if unable to read
- Signed informed consent if capable
- Legal guardians have received oral and written information and signed consent
- Beneficiary of a social security scheme
You will not qualify if you...
- Isolated extramedullary involvement at inclusion
- Patient of childbearing age without effective contraception
- Adult under legal protection (safeguard of justice, curatorship, guardianship) or deprived of liberty
AI-Screening
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Trial Site Locations
Total: 3 locations
1
CHU Angers
Angers, France
Actively Recruiting
2
CHU Brest
Brest, France
Actively Recruiting
3
CHU Rennes
Rennes, France
Actively Recruiting
Research Team
E
Elie COUSIN, Md
CONTACT
M
marie-laure gervais, phd
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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