Actively Recruiting
CHIME: Comparing Health Interventions for Maternal Equity
Led by Stanford University · Updated on 2026-03-05
795
Participants Needed
4
Research Sites
218 weeks
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum. The main question it aims to answer is which of the two multi-level, multi-component interventions has greater effectiveness in reducing maternal postpartum weight retention at 12-months postpartum. Hypothesis (primary): Both multi-level, multi-component interventions will have greater effectiveness reducing maternal postpartum weight retention at 12-months postpartum than the usual care group. Hypothesis (secondary): The community-based intervention will have greater effectiveness than the self-management intervention. Participants will be asked to participate in one of the study interventions from early pregnancy until 12 months postpartum and complete five research visits. General procedures include completion of: * Questionnaires * Dietary recalls * In-depth interviews * Anthropometric measurements * Collection of blood via finger stick or blood panel
CONDITIONS
Official Title
CHIME: Comparing Health Interventions for Maternal Equity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Maternal age 18 years or older
- Maternal gestational age 64 20 weeks with viable singleton pregnancy documented on first trimester ultrasound with an intention to continue pregnancy to term
- Plans to continue receiving antenatal care at the recruitment site/network
- Maternal characteristics include at least one of the following: self-identifies as Black/African American, self-identifies as Hispanic/Latino/a/e/x, or insured by Medicaid
- Maternal ability to speak English or Spanish
- Completion of baseline data collection (maternal survey data, weight, and height measurement prior to randomization)
You will not qualify if you...
- Age less than 18 years at baseline
- Underweight (BMI less than 18 kg/m2) at pre-pregnancy period
- Underlying disease or treatment that might impact weight status (e.g., significant gastrointestinal conditions, major psychiatric disorders, and others at the discretion of the study clinician)
- Unwillingness or inability to complete study visits or intervention components
- Unwillingness or inability to commit to intervention components for self or infant, including plans to move more than 100-mile radius from recruitment site
- Multiple gestations
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Stanford University
Palo Alto, California, United States, 94304
Active, Not Recruiting
2
New York Presbyterian Queens
Flushing, New York, United States, 11355
Actively Recruiting
3
Columbia University Medical Center
New York, New York, United States, 10012
Actively Recruiting
4
NYU Langone Health
New York, New York, United States, 10016
Actively Recruiting
Research Team
J
Jennifer Woo Baidal Associate Professor, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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