China-DECODE Study Early Diagnosis and Intervention for Cognitive Dysfunction in Type 2 Diabetes Patients

What this Trial Is About

This research aims to improve early diagnosis and intervention for cognitive dysfunction in people with type 2 diabetes, a condition linked to increased risk of memory and thinking problems, including dementia. The study addresses current challenges in clinical management, such as inconsistent diagnostic criteria and limited data sharing, by establishing a large population cohort with standardized information and biological samples. It also applies advanced brain imaging techniques to support precise diagnosis of cognitive issues in diabetes. Participants undergo naturalistic observation without experimental treatments. During the screening period, they complete neuropsychological tests and laboratory exams including brain MRI and olfactory function assessments. Biological samples like plasma, serum, urine, and feces are collected to build a high-quality sample bank. The study integrates uniform standards and advanced biological and clinical data collection to better understand cognitive dysfunction in type 2 diabetes. Throughout the study, participants cognitive function is evaluated using a comprehensive test battery. Researchers collect clinical and biological data to identify prevalence, risk factors, biomarkers, and optimal glycemic control related to cognitive decline in diabetes. The study runs from 2016 to 2034, providing long-term monitoring and data integration to support improved diagnosis and treatment strategies for this population.

China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)