Actively Recruiting
China Imaging-based Biobank of Cerebral Small Vessal Diseases
Led by Peking University Third Hospital · Updated on 2021-07-14
10000
Participants Needed
1
Research Sites
326 weeks
Total Duration
On this page
Sponsors
P
Peking University Third Hospital
Lead Sponsor
B
Beijing Tiantan Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to build a national image-based comprehensive evaluation platform of CSVD through longitudinal collection of imaging based medical data of patients with cerebral small vessel diseases (CSVD). On this basis, the new classification and diagnostic criteria of CSVD are proposed, and the risk prediction model of CSVD is established. By evaluating the prognostic factors of CSVD, early identification of high-risk CSVD population.
CONDITIONS
Official Title
China Imaging-based Biobank of Cerebral Small Vessal Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Presence of small vessel disease lesions visible on brain MRI, including:
- White matter hyperintensity with Fazekas score 2 or higher
- Fazekas score 1 with more than 2 vascular risk factors (such as hypertension, high cholesterol, diabetes, obesity, smoking, or other vascular events except stroke)
- Fazekas score 1 combined with lacunar focus
- Imaging showing new subcortical lacunar infarction
- Able to live independently in daily life (Modified Rankin Scale score 2 or less)
- Signed informed consent
You will not qualify if you...
- Acute cerebral infarction with lesions larger than 20 mm showing high signal on DWI
- Acute cerebral hemorrhage
- Acute subarachnoid hemorrhage or history of cerebrovascular malformation or aneurysmal subarachnoid hemorrhage
- Untreated aneurysms larger than 3 mm
- Diagnosed neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease
- Non-angiogenic white matter lesions, including multiple sclerosis, adult white matter dysplasia, metabolic encephalopathy
- Mental disorders diagnosed by DSM-V criteria
- Contraindications to MRI (e.g., claustrophobia)
- Severe organic diseases such as malignant tumors with expected survival less than 5 years
- Inability to cooperate to complete follow-up due to geographic or other reasons
- Participation in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking University Third Hospital
Beijing, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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