Actively Recruiting
China Lung Cancer Screening (CLUS) Study Version 3.0
Led by Shanghai Chest Hospital · Updated on 2022-08-09
100000
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
CLUS version 1.0, had proven that LDCT led to a 74.1% increase in detecting early-stage lung cancer compare to usual care (NCT02898441). CLUS version 2.0 evaluated the efficacy of new techniques (AI, AFI and MTB) in fostering the implementation of lung cancer screening (NCT03975504). The present multi-center study is performed to evaluate the effectiveness of different lung cancer screening strategy and validate our previous findings. 100,000 high-risk subjects (age 45-75) were recruited to take LDCT screening (Baseline + 2 biennial repeated LDCT screening). Follow-up for lung cancer incidence, lung cancer mortality and overall mortality was performed. Blood samples were stored in a Biobank. Management of positive screening test was carried out by a pre-specified protocol.
CONDITIONS
Official Title
China Lung Cancer Screening (CLUS) Study Version 3.0
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 45 to 75 years
- History of cigarette smoking of 20 or more pack-years, and if former smoker, quit within the last 15 years
- Family history of malignant tumors in immediate family members
- Personal history of cancer
- Professional exposure to carcinogens
- Long-term exposure to second-hand smoke
- Long-term exposure to cooking oil fumes
You will not qualify if you...
- Chest CT scan within the past 12 months
- History of any cancer within the last 5 years
AI-Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Chest hospital
Shanghai, Shanghai Municipality, China, 200030
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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