Actively Recruiting
China Takayasu Arteritis Registry (CTA Registry)
Led by Aimin Dang · Updated on 2016-11-16
1000
Participants Needed
1
Research Sites
517 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Takayasu arteritis (TA) is a chronic large-vessel vasculitis that mainly affects the aorta and its major branches. The epidemiology and pathophysiology of TA is still unclear in China, although many studies have been done. Our previous study supporting by National Natural Science Foundation of China indicated the cytokines such as hs-CRP, NT-proBNP and tumor necrosis factor-alpha (TNF-α) can be used to monitor TA activity, and HLA gene alleles were associated with TA in Chinese han population. Further investigations with larger samples are needed to fully understand the a pathophysiology of TA. The purpose of this study is to build a Chinese national registry system for TA to obtain real-world information, such as current status of characteristics, diagnosis, disease activity, the severity of disease, treatment and outcomes of Chinese TA patients. To analysis and development of effective disease monitoring and treatment strategies.
CONDITIONS
Official Title
China Takayasu Arteritis Registry (CTA Registry)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age at disease onset < 40 years (development of symptoms or findings related to Takayasu arteritis before 40 years old)
- Claudication of extremities (fatigue and discomfort in muscles of one or more extremities during use, especially upper limbs)
- Decreased brachial artery pulse (reduced pulse in one or both arms)
- Blood pressure difference >10 mm Hg between arms
- Bruit audible on listening over one or both subclavian arteries or abdominal aorta
- Arteriogram abnormality (narrowing or blockage of the aorta, its main branches, or large arteries in limbs not caused by arteriosclerosis or similar conditions)
You will not qualify if you...
- Vessel lesions entirely due to atherosclerosis
- Giant cell arteritis or other infectious forms of large vessel vasculitis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai Hospital
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
A
Aimin Dang, MD,PhD
CONTACT
N
Naqiang lv, MD,PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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