Actively Recruiting

All Genders
NCT05230017

Chinese AntiphosPholipid Syndrome cohorT cOllaborative NEtworks

Led by Peking Union Medical College Hospital · Updated on 2024-07-30

2000

Participants Needed

18

Research Sites

217 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombosis and pregnancy morbidity in patients with persistently positive antiphospholipid antibodies (aPLs). However, large-scale research on general population with persistent aPLs has been lacking. This project proposes to establish the first multicenter cohort of patients with persistently positive aPLs in China and conduct a comprehensive clinical phenotyping study. Based on traditional phenotypes of thrombotic and pregnancy events, the focus will be on extra-standard clinical phenotypes and prospective assessment of event risk and prognosis in aPL-positive population. A prospective analysis of extra-standard antibodies will also be conducted to recommend detection criteria for extra-standard antibody application in China and to assess their clinical significance.

CONDITIONS

Official Title

Chinese AntiphosPholipid Syndrome cohorT cOllaborative NEtworks

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of one or more antiphospholipid antibodies tested according to the 2006 Sapporo APS classification criteria on two or more occasions at least 12 weeks apart
Not Eligible

You will not qualify if you...

  • Patients who refuse to participate
  • Patients unable to be followed up

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 18 locations

1

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

2

Beijing Shunyi Hospital

Beijing, Beijing Municipality, China, 101300

Actively Recruiting

3

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

4

The Third Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China, 510150

Actively Recruiting

5

Shenzhen People's Hospital

Shenzhen, Guangdong, China, 518020

Actively Recruiting

6

The Second People's Hospital of Shenzhen

Shenzhen, Guangdong, China, 518035

Actively Recruiting

7

The First Affiliated Hospital of Guangxi Medical University

Nanning, Guangxi, China, 530021

Actively Recruiting

8

The Affilicated Hospital of Inner Mongolia Medical University

Hohhot, Inner Mongolia, China, 010110

Actively Recruiting

9

Jiangsu Province Hospital

Nanjing, Jiangsu, China, 210029

Actively Recruiting

10

The Second Affiliated Hospical of Nanchang University

Nanchang, Jiangxi, China, 330006

Actively Recruiting

11

The Second Affiliated Hospital of Dalian Medical University

Dalian, Liaoning, China, 116031

Actively Recruiting

12

The First Hospital of China Medical University

Shenyang, Liaoning, China, 110001

Actively Recruiting

13

Qilu Hospital of Shandong University

Jinan, Shandong, China, 250012

Actively Recruiting

14

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China, 200025

Actively Recruiting

15

Tianjin Medical University Genral Hospital

Tianjin, Tianjin Municipality, China, 300052

Actively Recruiting

16

First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, China, 650032

Actively Recruiting

17

First People's Hospital of Yunnan Province

Kunming, Yunnan, China, 650032

Actively Recruiting

18

The Second Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 311202

Actively Recruiting

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Research Team

J

Jiuliang Zhao, M.D.

CONTACT

Y

Yangzhong Zhou, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Chinese AntiphosPholipid Syndrome cohorT cOllaborative NEtworks | DecenTrialz