Evaluation of Risk and Bone Changes After Hip Fracture in Chinese Older Adults Using Quantitative CT

What this Trial Is About

Osteoporotic hip fractures pose significant risks for elderly individuals, often leading to disability and death. This research aims to observe and understand the factors influencing the risk of a second hip fracture, focusing on changes in proximal femoral bone density, structure, and surrounding muscle using quantitative computed tomography QCT. The study also seeks to differentiate between femoral neck fractures and trochanter fractures in terms of bone and muscle characteristics. Participants will undergo QCT scans using clinical CT scanners at participating centers to measure volumetric bone mineral density vBMD, bone structure, and muscle around the hip. The study is observational and prospective, with quality control and image interpretation centralized at Beijing Jishuitan Hospital. Researchers will analyze the QCT images to explore their value in predicting second hip fracture risk. During the study, participants will be monitored for hip re-fracture over three years and for all-cause mortality over two years. The study involves collecting detailed imaging data and clinical evaluations to assess bone and muscle health after the first hip fracture. This long-term follow-up helps understand the risk factors and outcomes associated with subsequent hip fractures in elderly osteoporotic patients.

Chinese Second Hip Fracture Evaluation