Comparing Chlorhexidine and Saline to Clean the Surgical Area During Colorectal Cancer Surgery A Multicenter, Randomized Controlled Study

What this Trial Is About

Researchers are evaluating the effectiveness of chlorhexidine compared to saline for flushing the surgical area during colorectal cancer surgery. This study aims to see if chlorhexidine irrigation can reduce surgical site infections and postoperative complications in patients undergoing colorectal cancer surgery. The trial includes diabetic and non-diabetic patients with either colon or rectal cancer, with a focus on surgical outcomes within 30 days after surgery. Participants will be randomly assigned to receive either chlorhexidine or saline irrigation after their colorectal cancer surgery. The chlorhexidine solution is applied to the surgical area for about one minute before the skin is sutured. The amount and duration of flushing may vary based on factors such as abdominal contamination, bleeding, and tumor invasion to ensure a clear surgical field free of blood, tissue fragments, or infection. During the study, researchers will monitor participants for surgical site infections and other postoperative complications within 30 days after surgery. The study uses a double-blind design to reduce bias. Participants must be between 18 and 85 years old, have resectable colorectal tumors confirmed by imaging, and meet certain health and anesthesia status criteria. They will be followed up to assess the number of infections and complications related to the surgery and irrigation method used.

Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery