Actively Recruiting
The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response
Led by University of Guelph · Updated on 2025-07-15
35
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are: * Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal? * What is the correlation between chewing behaviour, satiation, and changes in postprandial glucose, triacylglycerols, and satiety ratings? Participants will attend the research centre fasted on three occasions to consume an ad libitum meal, complete questionnaires, and provide fasting and postprandial finger prick blood samples.
CONDITIONS
Official Title
The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female aged 18 to 45 years
- Body mass index between 18.5 and 27.9 kg/m2 or waist circumference less than 88 cm
- No known food allergies or sensitivities
- Non-restrained eaters based on the Three Factor Eating Questionnaire
- No history of gastrointestinal diseases affecting eating or digestion
- Not taking medications that affect appetite, digestion, blood sugar, saliva, or chewing
- Stable medication use
- Non-smokers
- No significant weight changes in the past 3 months
- Regular monthly menstrual cycles
- Not pregnant, lactating, or post-menopausal
You will not qualify if you...
- Diabetes or metabolic disorders affecting blood sugar or heart health
- Any food allergies, intolerances, or sensitivities
- Life-threatening allergies
- Pregnant or breastfeeding
- Participation in another clinical trial
- More than 14 alcoholic drinks per week
- Current smokers or smoking history over 10 years
- Regular recreational drug use
- Restrained eaters (>15 on Three-Factor Eating Questionnaire)
- Unusual sleep patterns
- Irregular breakfast habits
- Recent or intended weight changes over 10% in last 6 months
- Use of medications affecting appetite, digestion, blood sugar, lipids, or chewing (except oral contraceptives)
- Dry mouth from any cause
- Diagnosed Sjogren's Syndrome
- Inability to follow study procedures
- Uncomfortable with finger prick blood sampling
- Avoids almonds or chocolate
- Temporomandibular joint disorder
- History of oral cancer
- Recent dental or jaw surgery
- Avoids hard foods due to dental concerns
- Has dentures, braces, Invisalign, or dental implants causing chewing difficulty
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Human Health Sciences
Guelph, Ontario, Canada, N1G 2G4
Actively Recruiting
Research Team
A
Amanda J Wright, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here