Registry of Optimal Transcatheter Treatments for Mitral Valve Insufficiency

What this Trial Is About

Researchers are studying clinical outcomes in patients undergoing transcatheter mitral valve replacement TMVR for mitral insufficiency. This multinational registry focuses on patients treated with TMVR in real-world practice and collects data on those who have undergone screening for TMVR. Some historical data include patients who received other treatments like edge-to-edge repair, mitral valve surgery, or medical therapy. The registry includes patients who successfully underwent TMVR with any device. Patients who failed TMVR screening and underwent other treatments such as mitral valve edge-to-edge repair, mitral valve surgery, or medical therapy were previously included but are no longer systematically enrolled. The study collects data over various timepoints to observe the effects of these therapies. Participants are followed for at least 30 days after treatment with echocardiography and clinical evaluations. Researchers measure mitral insufficiency severity, device-related complications within 30 days, and longer-term outcomes like mortality, rehospitalization for heart failure, and unplanned mitral valve interventions over 12 months. This observational registry aims to understand outcomes and safety in patients treated with TMVR and related therapies in routine care.

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry