Actively Recruiting
The Choice of Treatment Methods and Efficacy of LABC
Led by Peking Union Medical College Hospital · Updated on 2023-10-12
50
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the therapeutic effects of chemotherapy followed by surgery and surgery followed by chemotherapy in patients with locally advanced breast cancer（LABC). Patients with LABC will be randomly divided into two groups, each receiving chemotherapy followed by surgery or surgery followed by chemotherapy. The main comparison was between the disease-free survival (DFS) of two groups of patients, with the secondary study endpoint being overall survival (OS); Five year survival; Local recurrence or distant metastasis rate.
CONDITIONS
Official Title
The Choice of Treatment Methods and Efficacy of LABC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female aged 18 to 70 years
- Diagnosed with locally advanced breast cancer (stage IIIb to IIIc)
- Clinical or biopsy-confirmed breast cancer
- Tumor evaluated as potentially removable by surgery (ultrasound shows tumor not surrounding axillary vein)
- Accept treatment plans including surgery, radiotherapy, and chemotherapy
- Volunteer to participate and sign informed consent
- Willing to complete follow-up and quality of life and psychological assessments
You will not qualify if you...
- Younger than 18 or older than 70 years
- Previous breast cancer surgery, radiotherapy, or chemotherapy
- Not expected to undergo surgery, radiotherapy, or chemotherapy
- History of other malignant tumors
- Pregnant or breastfeeding
- Active infection or fever
- Serious diseases affecting trial compliance such as severe heart or lung problems, liver or kidney dysfunction, uncontrolled diabetes, or mental illness
AI-Screening
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Trial Site Locations
Total: 1 location
1
Ying Xu
Beijing, China, 100730
Actively Recruiting
Research Team
Y
Ying Xu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
2
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