Actively Recruiting
CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational Study
Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2025-04-03
2500
Participants Needed
1
Research Sites
84 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
CHOLE-POSSUM PRO is a prospective multicenter observational study on patients with ACC candidate to EC. The rationale of the study is to validate the CHOLE-POSSUM PRO SCORE for 30-day mortality in this population.
CONDITIONS
Official Title
CHOLE-POSSUM PRO Validation for Prediction of Mortality After Cholecystectomy for Acute Calculous Cholecystitis: Protocol for a Prospective Multicenter Observational Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute calculous cholecystitis as defined by TG18 criteria
- Candidate for early cholecystectomy during the initial hospital admission, including open cholecystectomy, early laparoscopic cholecystectomy, conversions, or bail-out procedures
- Age 18 years or older
- Stratified for risk of common bile duct stones using the Israelian Score and, if confirmed, received pre-operative ERCP
- Provided signed and dated informed consent form
- Willing to comply with all study procedures and be available for the study duration
You will not qualify if you...
- Pregnancy or lactation
- Acute cholecystitis not caused by gallstones
- Symptoms started more than 10 days before cholecystectomy (except if pre-operative ERCP done and EC within 10 days)
- Presence of pancreatitis
- Intraoperative treatment of common bile duct stones
- Any condition that increases risk or prevents full compliance or study completion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fondazione IRCCS Policlinico San Matteo
Pavia, Pavia, Italy, 27100
Actively Recruiting
Research Team
L
Luca Ansaloni, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here