Study on Multimorbidity Impact in Patients Hospitalized for COPD, Asthma, or Bronchiectasis Exacerbations

What this Trial Is About

Researchers are investigating how having multiple chronic conditions affects patients hospitalized due to flare-ups of chronic airway diseases CAD, including chronic obstructive pulmonary disease COPD, asthma, and bronchiectasis. This multicenter, observational study will follow at least 2,000 patients to better understand how these additional health issues influence hospital stay length, readmission rates, symptoms, lung function, quality of life, and healthcare use. Participants will be enrolled during their hospital stay for a CAD exacerbation, where detailed information such as medical history, lung tests, heart ultrasound, microbiology, imaging, and quality-of-life surveys will be collected. Blood and lung fluid samples will be taken for biomarker analysis. Patients will then be monitored closely over one year with follow-up visits at 1, 3, 6, 9, and 12 months to track disease progression, treatment adherence, exacerbations, and other health outcomes. Throughout the study, researchers will collect data on symptom scores, lung function tests, mental health, and healthcare costs. The main outcomes include hospital stay duration and rates of re-exacerbation within 12 months. Additional assessments include quality of life, mortality, imaging changes, medication use, and patterns of multiple medications. Data will be carefully managed and reviewed to ensure accuracy and contribute to improved care for CAD patients with multiple health conditions.

Chronic Airway Disease and Multimorbidity Cohort