Actively Recruiting
Chronic Coronary Syndrome in Swedish Primary Care
Led by Region Östergötland · Updated on 2026-01-30
500
Participants Needed
3
Research Sites
504 weeks
Total Duration
On this page
Sponsors
R
Region Östergötland
Lead Sponsor
L
Linkoeping University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn about a new procedure for investigation of possible coronary heart disease and to see if it is faster, cheaper or more expensive, promotes healthier behavior, mental well-being, adherence to drugs for heart protection and the risk for cardiac events like acute myocardial infarction over years to come. The novelty in the procedure is that a myocardial perfusion scan to assess blood flow to areas of the heart muscle, echocardiography i.e., heart ultrasound and heart CT scan comes as a "package investigation" performed on the same day. According to existing routines, "standard investigation" an exercise stress bicycle test is done, as well as an echocardiography and if needed the work up is completed by a myocardial perfusion scan. The main questions the trial aims to answer are: * are the results from the procedure given to the patient faster with package investigation as compared to standard investigation? * does the cost differ between the package and standard investigation group? * does self-reported physical activity, physical fitness, dietary habits and mental well-being differ between the package and standard investigation group at start and after one, three and five years? * does prescription of drugs taken for heart protection and adherence to the prescribed drugs differ between the package and standard investigation group after two and five years? * does the risk for heart events like acute heart infarction differ between package and standard investigation after two and five years? Primary health care centers in Region Östergötland are randomly assigned to use either the new or existing procedure for investigation of possible coronary heart disease a so called cluster randomization. Patients who consult a physician at any of these primary health care centers are potential participants in the trial and are informed about the trial by written information, as they get their appointment for the medical investigation at either of two hospitals in the Region Östergötland. When the patient comes to the hospital for the investigations, he or she is asked to give written consent to the research i.e., to answer questionnaires now after one, three and five years, to let the researchers take part of the medical records, investigational results and data from medical registries over time.
CONDITIONS
Official Title
Chronic Coronary Syndrome in Swedish Primary Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
• People who seek primary care for symptoms judged to be compatible with a medium probability (PTP> 15) for symptomatic chronic coronary artery disease.
You will not qualify if you...
- Suspicion of acute coronary syndrome when care is sought.
- Previously diagnosed acute myocardial infarction
- Revascularization with PCI/CABG
- Proven reversible ischemia according to myocardial scintigraphy.
- Left Bundle Branch Block (LBBB).
- Ventricular pacemaker
- People whose meaning due to illness, mental disorder, weakened state of health or any other similar condition cannot be obtained, to be included in a research project.
- Insufficient understanding of spoken and written Swedish language.
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Department of Clinical Physiology, Linköping University Hospital, Linköping
Linköping, Sweden, S-58185
Actively Recruiting
2
Hjärthälsan Linköping AB
Linköping, Sweden, S-582 18
Actively Recruiting
3
Department of Clinical Physiology, Vrinnevi Hospital
Norrköping, Sweden, S-601 82
Actively Recruiting
Research Team
F
Fredrik Iredahl, MD PhD
CONTACT
S
Staffan Nilsson, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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