Actively Recruiting
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
Led by Federal University of Minas Gerais · Updated on 2026-03-24
25
Participants Needed
1
Research Sites
89 weeks
Total Duration
On this page
Sponsors
F
Federal University of Minas Gerais
Lead Sponsor
M
Max Nutri
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption. The main questions it aims to answer are: * In women with constipation who do not consume adequate dietary fiber, does supplementation help improve bowel function? * Among the fibers studied, is there any hierarchy of effect in the treatment of constipation (i.e., is one more effective than the other)? The researchers will compare the effects of the two dietary fibers against each other and against a control to evaluate their impact. Participants will: * Consume 20 g of fiber daily for 6 days, divided into two doses of 10 g each. * Attend a nuclear medicine visit at the end of each 6-day fiber period to perform scintigraphy. * Keep a daily record of bowel habits and dietary intake.
CONDITIONS
Official Title
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female participants aged 18-59 years.
- Willingness to sign the Informed Consent Form.
- No restrictions on the consumption of egg or gluten.
- No history or diagnosis of gastrointestinal diseases other than functional constipation.
- Non-smokers.
- No use of prebiotics, probiotics, synbiotics, or antibiotics at least 10 days prior to the study.
- No previous surgery affecting gastrointestinal transit.
- Willingness to discontinue the use of laxatives at least 4 days prior to scintigraphic imaging.
- Participants who do not consume adequate dietary fiber (25-30 g/day) as assessed by dietary recall.
- No confirmed or suspected pregnancy during the study.
- No self-reported menopause
You will not qualify if you...
- Diagnosis of diabetes, severe hyperthyroidism, or hypothyroidism.
- Use of opioid medications.
- Delayed gastric emptying at 4 hours during the placebo period (participants meeting this criterion will be excluded from final analysis).
AI-Screening
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Trial Site Locations
Total: 1 location
1
School of Nursing, Federal University of Minas Gerais
Belo Horizonte, Minas Gerais, Brazil, 30130-100
Actively Recruiting
Research Team
S
Simone de Vasconcelos Generoso, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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