Actively Recruiting

Age: 0 - 21Years
All Genders
NCT04725422

CHronic Nonbacterial Osteomyelitis International Registry

Led by Seattle Children's Hospital · Updated on 2024-07-30

2000

Participants Needed

1

Research Sites

1669 weeks

Total Duration

On this page

Sponsors

S

Seattle Children's Hospital

Lead Sponsor

B

Boston Children's Hospital, Boston, MA, USA

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.

CONDITIONS

Official Title

CHronic Nonbacterial Osteomyelitis International Registry

Who Can Participate

Age: 0 - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age at enrollment is equal to or younger than 21 years of age
  • Presence of bone edema on STIR or T2 fat saturation sequence on MRI within 12 weeks of enrollment
  • Whole body imaging evaluation (either WB MRI or bone scintigraphy)
  • Bone biopsy to exclude infection or malignancy unless bone lesions follow typical distribution or there is IBD, psoriasis, or palmar plantar pustulosis
Not Eligible

You will not qualify if you...

  • History of or current malignancy
  • Current infectious osteomyelitis
  • Contraindication to the selected treatment agent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Seattle Children's Hospital

Seattle, Washington, United States, 98105

Actively Recruiting

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Research Team

Y

Yongdong (Dan) Zhao, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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CHronic Nonbacterial Osteomyelitis International Registry | DecenTrialz