Actively Recruiting
Chronic Post-leptospirosis Manifestations in Reunion
Led by Centre Hospitalier Universitaire de la Réunion · Updated on 2023-08-31
198
Participants Needed
4
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Leptospirosis is a bacterial infection transmitted to humans through contact with water or soil contaminated by animal urine, posing a significant public health concern. This research focuses on patients in Reunion, where leptospirosis is more common due to climate factors. The study aims to identify factors linked to the severity of leptospirosis and investigate long-term effects, including symptoms persisting beyond one year after infection. The study involves biological sampling including blood and urine collection for serology tests, freezing and storage of serum samples, and collecting clinical and biological data. Patients previously hospitalized with confirmed leptospirosis within 12 to 18 months are followed up. Two medical visits and two telephone interviews will assess quality of life and other health aspects over a year, with plans to monitor outcomes up to two years. Participants will have blood and urine samples collected and will be asked to complete telephone questionnaires. The study measures the proportion of patients experiencing chronic symptoms two years after infection, tracking clinical, serological, and quality of life outcomes. Data collection occurs through dedicated electronic forms, with participant follow-up lasting up to two years to better understand chronic manifestations of leptospirosis.
CONDITIONS
Brief Title
Chronic Post-leptospirosis Manifestations in Reunion
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult or child subjects having been included in the COLEPT cohort with confirmed leptospirosis
- Hospitalized for leptospirosis confirmed within 12-18 months before inclusion
- Resident of Reunion
- Ability to answer a telephone questionnaire
- Covered by a social security scheme
You will not qualify if you...
- Refusal to participate by patient or representative if patient cannot give opinion
- Exclusion or early termination from the COLEPT cohort
- Under judicial safeguard, guardianship, curatorship, or family authorization under protection mandate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single visit
Participants provide biological samples including whole blood and urine for serology and other analyses, and clinical data are collected.
1 visit (in-person)
Trial Site Locations
Total: 4 locations
1
CHOR
Saint-Paul, France
Actively Recruiting
2
DIALLO
Saint-Pierre, France, 97410
Actively Recruiting
3
GHER
Saint-Benoît, Reunion, 97470
Actively Recruiting
4
CHU de la Réunion
Saint-Denis, Reunion, 97400
Actively Recruiting
Research Team
L
Loic RAFFRAY, Dr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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