Actively Recruiting
Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers
Led by Rachel A. Moses · Updated on 2026-01-26
100
Participants Needed
1
Research Sites
295 weeks
Total Duration
On this page
Sponsors
R
Rachel A. Moses
Lead Sponsor
D
Dartmouth-Hitchcock Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
Collection of urine, blood, and tissue samples from patients undergoing hyperbaric oxygen therapy
CONDITIONS
Official Title
Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years of age
- For Cohort 1: Post pelvic radiation with moderate to severe radiation cystitis and recurrent visible blood in urine without infection or cancer, confirmed by specialists and tests
- Scheduled to start or have started HBOT within the past 7 days as standard care for radiation cystitis (Cohort 1)
- At least 18 years of age without history of pelvic radiation and scheduled to start or have started HBOT within past 7 days for reasons other than bladder inflammation (Cohort 2)
- At least 18 years of age without history of pelvic radiation or HBOT (Cohort 3)
- At least 18 years of age similar to Cohort 1 but opting out of HBO therapy (Cohort 4)
You will not qualify if you...
- Pregnant or lactating females
- Uncompensated heart failure, fluid overload, or recent myocardial infarction preventing HBOT
- History of uncontrolled seizure disorder, active urinary tract infection, active Grave's disease, cystic fibrosis, sickle cell anemia, known HIV, or autoimmune disease needing active steroid or immunomodulating treatment
- Refusal to sign informed consent
- Prior participation in clinical trials affecting immune status
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Actively Recruiting
Research Team
R
Rachel Moses, MD
CONTACT
A
Amanda Wittemann
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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