Study Comparing Middle Meningeal Artery Embolization and Conventional Surgery in Adults Aged 40 to 90 with Chronic Subdural Hematoma

What this Trial Is About

This trial investigates whether middle meningeal artery embolization MMAE can be a safe and effective alternative to conventional open surgery for patients with moderately symptomatic chronic subdural hematoma CSDH. The study aims to determine if MMAE reduces the need for additional rescue surgery or deaths compared to standard surgery and to assess the safety of both treatments in this patient group. Participants will be randomly assigned to receive either MMAE, which involves particle embolization of the middle meningeal artery using specialized devices, or conventional surgery through burr holes or craniotomy to drain the hematoma. Treatments are delivered soon after randomization, and participants in both groups are monitored closely for outcomes. During the study, participants will share medical history, undergo physical exams, blood tests, and head CT scans. They will also complete questionnaires and report any adverse events. Researchers will follow participants for about 180 to 210 days after treatment to measure the need for rescue surgery or death and evaluate treatment safety. This process includes regular evaluations to track progress and health status.

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study