Effectiveness of Transgrade vs Interlaminar Epidural Steroid Injection for Chronic Unilateral Lumbar Radicular Pain

What this Trial Is About

Chronic neuropathic lumbar pain is a common and challenging condition affecting many patients, often causing persistent leg and back pain. This trial compares two approaches for managing this pain: Transgrade (TG) epidural steroid injection, a new technique using a special angled needle without extra equipment, and Interlaminar (IL) epidural steroid injection, which delivers medication between adjacent vertebrae. The study aims to evaluate which method provides better pain relief for people who have not responded well to conventional treatments. Participants will be randomly assigned to receive either the Transgrade or Interlaminar epidural steroid injection. Both procedures involve delivering steroid medication into the epidural space of the lower spine but use different needle techniques. The study is double-blinded, meaning neither participants nor researchers will know which treatment is given. The primary outcome is the number of patients experiencing successful pain relief measured at three months after the intervention, with follow-up extending to six months. During the study, participants will be monitored regularly to assess pain relief and any side effects. Pain intensity will be measured using a numeric rating scale, and medical evaluations will ensure ongoing safety. Participants must have a history of persistent unilateral leg and back pain for more than six months and an unsatisfactory response to standard therapies. The total study period includes treatment and follow-up visits over six months to gather comprehensive data on treatment effectiveness and safety.

Chronic Unilateral Lumbar Radicular Pain