Actively Recruiting
Chronic Wounds and Blood Circulation Detection
Led by National Health Research Institutes, Taiwan · Updated on 2026-01-09
425
Participants Needed
1
Research Sites
173 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and quality of life but also potentially increase medical costs and caregiving expenses. Traditional treatment methods often employ medications to enhance blood circulation, but these clinical approaches have limited effectiveness and induce the risk of side effects. Utilizing exercise as an intervention strategy can help improve lower limb blood circulation in the elderly while reducing the side effects associated with medications. However, due to physical frailty, elderly individuals often cannot participate in high-intensity exercises to improve their circulatory performance. Therefore, this study will develop a lower limb circulation enhancement exercise system to improve the circulatory performance in individuals with poor lower limb circulation. It will compare the effects of lower limb circulation enhancement exercise, vibration exercise, and mixed exercise on improving blood circulation and functional performance in the elderly or individuals with poor lower limb circulation. Participants will be randomly assigned into three groups: the lower limb circulation enhancement exercise group, the vibration exercise group, and the mixed exercise group. In addition, a separate group of young adults (control group) will serve as a reference for baseline comparisons. Initially, all participants will undergo a one-time exercise test, followed by a 12-week intervention. The lower limb circulation enhancement exercise group will perform a 30-minute leg press rowing exercise three times a week, while the vibration exercise group will engage in vibration exercise at the same frequency, and the mixed exercise group will perform group-based mixed exercise training at the same frequency. The young adult control group will not receive any intervention but will undergo the same assessments. Outcome evaluations before and after the intervention include lower limb blood perfusion monitoring, pain scales, and functional performance assessments.
CONDITIONS
Official Title
Chronic Wounds and Blood Circulation Detection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willingness to participate and comply with study procedures
- Ability to perform basic physical activities and complete lower limb circulation and functional assessments
- Normal cognitive function to understand instructions and provide informed consent
- Young Adults (Control Group): Aged 20-40 years, healthy with no chronic diseases or peripheral circulation disorders
- Older Adults (Healthy Elderly Group): Aged 65-95 years, no major chronic diseases affecting lower limb circulation
- Older Adults with Chronic Disease (Impaired Circulation Group): Aged 65-95 years, diagnosed with conditions impairing peripheral circulation such as peripheral arterial disease, chronic venous insufficiency, diabetes, hypertension, or hyperlipidemia
You will not qualify if you...
- Recent acute lower limb injury causing tissue exudation, swelling, or conditions preventing safe participation in assessments or interventions
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Center for Geriatrics and Welfare Research, National Health Research Institutes
Taipei, Taiwan
Actively Recruiting
Research Team
P
Po-Jung Chen, Ph.D.
CONTACT
C
Chueh-Ho Lin, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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