Actively Recruiting

Phase Not Applicable
Age: 20Years - 95Years
All Genders
Healthy Volunteers
NCT07330635

Chronic Wounds and Blood Circulation Detection

Led by National Health Research Institutes, Taiwan · Updated on 2026-01-09

425

Participants Needed

1

Research Sites

173 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and quality of life but also potentially increase medical costs and caregiving expenses. Traditional treatment methods often employ medications to enhance blood circulation, but these clinical approaches have limited effectiveness and induce the risk of side effects. Utilizing exercise as an intervention strategy can help improve lower limb blood circulation in the elderly while reducing the side effects associated with medications. However, due to physical frailty, elderly individuals often cannot participate in high-intensity exercises to improve their circulatory performance. Therefore, this study will develop a lower limb circulation enhancement exercise system to improve the circulatory performance in individuals with poor lower limb circulation. It will compare the effects of lower limb circulation enhancement exercise, vibration exercise, and mixed exercise on improving blood circulation and functional performance in the elderly or individuals with poor lower limb circulation. Participants will be randomly assigned into three groups: the lower limb circulation enhancement exercise group, the vibration exercise group, and the mixed exercise group. In addition, a separate group of young adults (control group) will serve as a reference for baseline comparisons. Initially, all participants will undergo a one-time exercise test, followed by a 12-week intervention. The lower limb circulation enhancement exercise group will perform a 30-minute leg press rowing exercise three times a week, while the vibration exercise group will engage in vibration exercise at the same frequency, and the mixed exercise group will perform group-based mixed exercise training at the same frequency. The young adult control group will not receive any intervention but will undergo the same assessments. Outcome evaluations before and after the intervention include lower limb blood perfusion monitoring, pain scales, and functional performance assessments.

CONDITIONS

Official Title

Chronic Wounds and Blood Circulation Detection

Who Can Participate

Age: 20Years - 95Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Willingness to participate and comply with study procedures
  • Ability to perform basic physical activities and complete lower limb circulation and functional assessments
  • Normal cognitive function to understand instructions and provide informed consent
  • Young Adults (Control Group): Aged 20-40 years, healthy with no chronic diseases or peripheral circulation disorders
  • Older Adults (Healthy Elderly Group): Aged 65-95 years, no major chronic diseases affecting lower limb circulation
  • Older Adults with Chronic Disease (Impaired Circulation Group): Aged 65-95 years, diagnosed with conditions impairing peripheral circulation such as peripheral arterial disease, chronic venous insufficiency, diabetes, hypertension, or hyperlipidemia
Not Eligible

You will not qualify if you...

  • Recent acute lower limb injury causing tissue exudation, swelling, or conditions preventing safe participation in assessments or interventions

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Center for Geriatrics and Welfare Research, National Health Research Institutes

Taipei, Taiwan

Actively Recruiting

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Research Team

P

Po-Jung Chen, Ph.D.

CONTACT

C

Chueh-Ho Lin, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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