Actively Recruiting
CIED Infection Quality Initiative Demonstration Project
Led by Duke University · Updated on 2026-05-06
200
Participants Needed
3
Research Sites
203 weeks
Total Duration
On this page
Sponsors
D
Duke University
Lead Sponsor
D
Duke Clinical Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this Quality Initiative (QI) demonstration project is to develop a model to increase guideline-driven care for patients with cardiovascular implantable electronic devices (CIED) infection. Multidisciplinary teams will be established to carry out the multifaceted intervention. This program seeks to improve early identification and diagnosis, appropriate treatment, and faster time to treatment of CIED infection.
CONDITIONS
Official Title
CIED Infection Quality Initiative Demonstration Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Have a cardiovascular implantable electronic device (CIED) in place
- Presumed CIED infection defined by either two or more positive blood cultures for typical skin organisms or one positive blood culture for other microorganisms with no other infection source
- Definite pocket infection signs such as localized redness, swelling, pain, tenderness, warmth, erosion, or drainage, even if cultures are negative due to prior antibiotic treatment
You will not qualify if you...
- Patients unsuitable for device extraction, for example those with do-not-attempt-resuscitation orders not on survival-prolonging therapy
- Death within one week of confirmed CIED systemic infection diagnosis or positive blood culture
- Patients with bacteremia from sources other than the CIED that resolved without evidence of device infection
- Patients with left ventricular assist devices (LVADs)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Northwestern
Chicago, Illinois, United States, 60611
Actively Recruiting
2
Atrium Health
Charlotte, North Carolina, United States, 28203
Not Yet Recruiting
3
Moses Cone
Greensboro, North Carolina, United States, 27401
Not Yet Recruiting
Research Team
K
Kimberly Ward, MPH
CONTACT
S
Sarah Brady
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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