Actively Recruiting

Phase Not Applicable
Age: 18Years - 24Years
All Genders
Healthy Volunteers
ID07162935

Addiction Potential, Flavoring Content, and Substitutability of Concept Flavored Cigarillos among Young Adult Cigarillo Users

Led by University of Oklahoma · Updated on 2026-05-11

300

Participants Needed

2

Research Sites

12 weeks

Total Duration

On this page

Sponsors

U

University of Oklahoma

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating cigar smoking behavior among young adults aged 18 to 24 who currently use cigarillos. The study aims to understand how different flavored cigarillos, including concept, characterizing, and tobacco flavors, influence smoking appeal, addiction potential, and possible quitting or switching behaviors under various flavor ban scenarios. This research will help clarify the role of flavor additives and ingredients in tobacco use and perceptions. Participants will be randomly assigned to smoke one of three types of cigarillos: concept flavored, characterizing flavored, or tobacco flavored. They will use one of three cigarillo brands while researchers assess their puffing behavior, subjective effects like satisfaction and taste, and exhaled carbon monoxide levels. The study includes an Experimental Tobacco Marketplace to simulate purchasing decisions and product substitution or quitting under different regulatory scenarios. During approximately two weeks from enrollment to the final smoking visit, participants' puff numbers and subjective rewards from smoking will be measured. Researchers will track smoking behavior and product appeal through surveys and laboratory assessments. The study requires participants to abstain from nicotine or tobacco for at least 12 hours before visits and monitors adherence to study procedures. Overall participation lasts about two weeks, focusing on detailed smoking and perception outcomes.

CONDITIONS

Brief Title

Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)

Who Can Participate

Age: 18Years - 24Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18 to 24
  • Report past 30-day use of a cigarillo
  • Ability to read English at least an 8th grade level
  • No immediate plans to quit using tobacco
  • At least 1 prior experience with a flavored tobacco product
  • U.S. Citizen or permanent resident of the United States
Not Eligible

You will not qualify if you...

  • Current use of smoking cessation pharmacotherapy or nicotine replacement therapy
  • Pregnant, planning to become pregnant, or currently breastfeeding
  • Past or current clinically significant heart disease or hypertension, or other smoking-related disease that could preclude successful study completion
  • Inability to abstain from nicotine/tobacco products for at least 12 hours
  • Unwillingness to use the research cigarillos in the lab

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - Approximately 2 weeks

Participants smoke assigned cigarillos of different flavors to assess puffing behavior, subjective effects, and exhaled carbon monoxide.

Multiple visits during the 2-week smoking period

Trial Site Locations

Total: 2 locations

1

University of Oklahoma Health Campus

Oklahoma City, Oklahoma, United States, 73104

Actively Recruiting

2

West Virginia University

Morgantown, West Virginia, United States, 26506

Not Yet Recruiting

Loading map...

Research Team

P

Project Manager

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

Similar Trials

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here