Actively Recruiting
Addiction Potential, Flavoring Content, and Substitutability of Concept Flavored Cigarillos among Young Adult Cigarillo Users
Led by University of Oklahoma · Updated on 2026-05-11
300
Participants Needed
2
Research Sites
12 weeks
Total Duration
On this page
Sponsors
U
University of Oklahoma
Lead Sponsor
N
National Institute on Drug Abuse (NIDA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating cigar smoking behavior among young adults aged 18 to 24 who currently use cigarillos. The study aims to understand how different flavored cigarillos, including concept, characterizing, and tobacco flavors, influence smoking appeal, addiction potential, and possible quitting or switching behaviors under various flavor ban scenarios. This research will help clarify the role of flavor additives and ingredients in tobacco use and perceptions. Participants will be randomly assigned to smoke one of three types of cigarillos: concept flavored, characterizing flavored, or tobacco flavored. They will use one of three cigarillo brands while researchers assess their puffing behavior, subjective effects like satisfaction and taste, and exhaled carbon monoxide levels. The study includes an Experimental Tobacco Marketplace to simulate purchasing decisions and product substitution or quitting under different regulatory scenarios. During approximately two weeks from enrollment to the final smoking visit, participants' puff numbers and subjective rewards from smoking will be measured. Researchers will track smoking behavior and product appeal through surveys and laboratory assessments. The study requires participants to abstain from nicotine or tobacco for at least 12 hours before visits and monitors adherence to study procedures. Overall participation lasts about two weeks, focusing on detailed smoking and perception outcomes.
CONDITIONS
Brief Title
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18 to 24
- Report past 30-day use of a cigarillo
- Ability to read English at least an 8th grade level
- No immediate plans to quit using tobacco
- At least 1 prior experience with a flavored tobacco product
- U.S. Citizen or permanent resident of the United States
You will not qualify if you...
- Current use of smoking cessation pharmacotherapy or nicotine replacement therapy
- Pregnant, planning to become pregnant, or currently breastfeeding
- Past or current clinically significant heart disease or hypertension, or other smoking-related disease that could preclude successful study completion
- Inability to abstain from nicotine/tobacco products for at least 12 hours
- Unwillingness to use the research cigarillos in the lab
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Approximately 2 weeks
Participants smoke assigned cigarillos of different flavors to assess puffing behavior, subjective effects, and exhaled carbon monoxide.
Multiple visits during the 2-week smoking period
Trial Site Locations
Total: 2 locations
1
University of Oklahoma Health Campus
Oklahoma City, Oklahoma, United States, 73104
Actively Recruiting
2
West Virginia University
Morgantown, West Virginia, United States, 26506
Not Yet Recruiting
Research Team
P
Project Manager
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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