Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
ID07348679

A Randomized Trial of Charcoal-filtered Cigarettes on Product Perceptions, Smoking Behaviors, and Toxicant Exposure

Led by Rutgers, The State University of New Jersey · Updated on 2026-06-05

252

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

R

Rutgers, The State University of New Jersey

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating how charcoal-filtered cigarettes affect smokers' perceptions, smoking habits, and exposure to harmful tobacco substances. The study aims to find out if people view charcoal-filtered cigarettes differently, smoke them in a different way than conventional filtered cigarettes, and whether this changes their exposure to harmful chemicals. This is a 5-week laboratory-based randomized trial involving adult smokers. Participants will start with a 7-day baseline period smoking their usual preferred brand. Then they will be randomly assigned to smoke either charcoal-filtered cigarettes with marketing (Natural American Spirit Sky), charcoal-filtered cigarettes without marketing (Tareyton), or conventional non-charcoal-filtered cigarettes (Natural American Spirit Yellow) for 4 weeks. Throughout the study, participants will complete weekly sessions where they smoke two cigarettes in a lab setting, provide urine and carbon monoxide samples, and complete questionnaires. During the 5-week study, researchers will assess various outcomes including risk beliefs, perceived health risks, subjective ratings, daily cigarette consumption, smoking behavior details (such as puff count and duration), carbon monoxide levels, and exposure to tobacco-related toxicants. Secondary measures include cravings, withdrawal symptoms, attitudes, intentions, and cigarette purchase behavior. The study involves regular monitoring and assessments across the 35-day period to understand the impact of cigarette filter types on smoking experiences and exposure.

CONDITIONS

Brief Title

Cigarette Filter Study

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female smokers aged 21 years or older
  • Self-report smoking at least 5 cigarettes per day for at least the past 6 months
  • Primarily smoke non-menthol cigarettes of brands other than Natural American Spirit
  • Not currently undergoing smoking cessation treatment or trying to quit
  • Able to communicate fluently in English (speaking, reading, and writing)
  • Capable of giving written informed consent and complying with study requirements
Not Eligible

You will not qualify if you...

  • Use of menthol or Natural American Spirit cigarettes as preferred or regular brand (over 20% of the time)
  • Enrollment or plans to enroll in a smoking cessation program within the next month
  • Initial carbon monoxide reading below 5 parts per million
  • History of substance abuse (other than nicotine) within the past 12 months or current treatment for substance abuse
  • Current alcohol consumption exceeding 25 standard drinks per week
  • Women who are pregnant, planning pregnancy, or lactating
  • Visual, physical, neurological impairments preventing completion of study procedures
  • Color blindness
  • Serious or unstable disease within the past 12 months (e.g., heart disease, cancer)
  • Lifetime history or current diagnosis of psychosis, bipolar disorder, or schizophrenia
  • Current diagnosis of major depression (history allowed if remission for 6 months or longer)
  • Significant non-compliance with protocol or study design
  • Participation in another research program that could impact study data
  • Any medical condition or medication that could compromise safety or study performance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Baseline Period

Duration - 7 days

Participants smoke their own preferred brand of cigarettes for 7 days to establish baseline smoking behavior.

1 baseline visit

Outpatient Treatment

Duration - 28 days

Participants are randomly assigned to smoke one of three types of cigarettes (charcoal-filtered with marketing, charcoal-filtered without marketing, or non-charcoal filtered) for 28 days.

Weekly visits for up to 4 weeks

Follow-up

Duration - 1 week

Participants complete assessments measuring smoking behaviors, perceptions, and toxicant exposure after the treatment period.

1 follow-up visit

Trial Site Locations

Total: 1 location

1

Institute for Nicotine and Tobacco Studies

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

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Research Team

M

Matthew Joy, MPH

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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