Actively Recruiting
Cigarette Filter Study
Led by Rutgers, The State University of New Jersey · Updated on 2026-04-24
252
Participants Needed
1
Research Sites
244 weeks
Total Duration
On this page
Sponsors
R
Rutgers, The State University of New Jersey
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overall purpose of this study is to determine the effects of using charcoal-filtered cigarettes on product perceptions, smoking behaviors, and biomarkers of exposure to tobacco-related toxicants. The main questions it aims to answer are: Do perceptions of cigarettes differ by their filter? Do people smoke charcoal-filtered cigarettes differently than cigarettes with conventional filters, and does this change their exposure to cigarette harms? Study participants will complete a 5-week laboratory-based, open-label, parallel-design randomized trial. After a baseline period of smoking their preferred brand, participants will smoke charcoal-filtered or non-charcoal-filtered cigarettes for 4 weeks while completing weekly sessions to assess primary outcomes. During weekly sessions, they will smoke two cigarettes in our laboratory, provide urine and carbon monoxide samples, and complete questionnaires.
CONDITIONS
Official Title
Cigarette Filter Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female smokers at least 21 years old who have smoked at least 5 cigarettes per day for the past 6 months
- Primarily smoke non-menthol cigarettes of brands other than Natural American Spirit
- Not currently undergoing smoking cessation treatment or trying to quit
- Able to communicate fluently in English (speaking, writing, reading)
- Capable of giving written informed consent and complying with study requirements
You will not qualify if you...
- Use of menthol or Natural American Spirit cigarettes as preferred brand more than 20% of the time
- Enrollment or plans to enroll in a smoking cessation program in the next month
- Initial carbon monoxide reading less than 5 ppm
- History of substance abuse (other than nicotine) in past 12 months or currently receiving treatment for substance abuse
- Current alcohol use exceeding 25 standard drinks per week
- Women who are pregnant, planning pregnancy, or lactating
- Visual, physical, neurological impairments preventing study procedures
- Color blindness
- Serious or unstable disease in past 12 months (e.g., heart disease, cancer)
- Lifetime or current diagnosis of psychosis, bipolar disorder, or schizophrenia
- Current diagnosis of major depression (history of major depression in remission for 6 months or more allowed)
- Significant non-compliance with protocol or study design
- Enrollment in other research that could impact study data
- Any medical condition or medication that could compromise safety or study performance
AI-Screening
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Trial Site Locations
Total: 1 location
1
Institute for Nicotine and Tobacco Studies
New Brunswick, New Jersey, United States, 08901
Actively Recruiting
Research Team
M
Matthew Joy, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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