Actively Recruiting
Cilostazol vs. Aspirin in Acute Non-cardioembolic Stroke With Cerebral mIcrobleeds
Led by Zhejiang Provincial People's Hospital · Updated on 2024-07-31
848
Participants Needed
1
Research Sites
371 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this clinical trial is to demonstrate that cilostazol is non-inferior to aspirin in terms of efficacy and safety for the secondary prevention of stroke in patients with acute non-cardioembolic ischemic stroke who have concurrent microbleeds. Researchers will compare the medication cilostazol with aspirin to assess its efficacy and safety in these patients. Participants will: Take the medication cilostazol or aspirin daily as part of an antiplatelet drug therapy. Have baseline data and follow-up data collected at the time of hospital admission, and then at 3 months, 6 months post-discharge, and annually thereafter up to 4 years. Have the primary endpoint set as stroke recurrence, with secondary endpoints being composite vascular events. Safety events will include moderate to severe hemorrhage and bleeding at any site.
CONDITIONS
Official Title
Cilostazol vs. Aspirin in Acute Non-cardioembolic Stroke With Cerebral mIcrobleeds
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute ischemic stroke within 1 month of onset
- Non-cardioembolic stroke
- Presence of cerebral microbleeds confirmed by susceptibility-weighted imaging
You will not qualify if you...
- Previous diagnosis of cerebral amyloid angiopathy according to Boston 2.0 criteria
- History of intracerebral hemorrhage suspected to be caused by cerebral amyloid angiopathy
- Severe adverse reactions to aspirin or cilostazol leading to non-compliance
- Need for combined anticoagulant therapy
- Need for long-term dual antiplatelet therapy for more than 1 month
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China, 310014
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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