Actively Recruiting

Age: 18Years +
All Genders
ID00882167

Sensitivity and Predictive Value of Functional Cine MRI Detecting Intra-abdominal Adhesions in Patients Undergoing Reoperation

Led by Radboud University Medical Center · Updated on 2025-01-15

100

Participants Needed

5

Research Sites

869 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the accuracy of functional cine magnetic resonance imaging (MRI) in detecting and mapping internal abdominal adhesions. Adhesions commonly form after abdominal surgery as part of healing but can cause complications like chronic pain, bowel obstruction, and difficulties during repeat surgeries. Currently, no validated imaging method exists to reliably map these adhesions before surgery. The study uses a CineMRI scan of the abdomen performed at 1.5 Tesla to identify adhesions. The main goal is to measure how sensitive and specific this imaging technique is at detecting adhesions between the abdominal wall and other tissues. The trial is designed as a prospective multicenter observational study involving patients undergoing reoperation, focusing on both adhesion presence and location. Participants will receive the CineMRI scan, and researchers will compare imaging results to surgical findings to evaluate accuracy. The primary measurement is sensitivity and specificity after 2 weeks. Approximately 100 patients are expected to enroll, with the study completing by December 2019. The trial monitors how well the MRI detects adhesions to the abdominal wall and between organs without additional interventions or treatments.

CONDITIONS

Official Title

Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a median abdominal scar from previous open abdominal surgery at least 10 cm long
  • Patients who have provided written consent
Not Eligible

You will not qualify if you...

  • Severe claustrophobia
  • Any condition preventing MRI scanning

AI-Screening

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Trial Site Locations

Total: 5 locations

1

Rijnstate Hospital

Arnhem, Gelderland, Netherlands

Not Yet Recruiting

2

Radboud University Nijmegen Medical Center

Nijmegen, Gelderland, Netherlands

Actively Recruiting

3

Jeroen Bosch Hospital

's-Hertogenbosch, Netherlands

Not Yet Recruiting

4

Gelre Hospital

Apeldoorn, Netherlands

Not Yet Recruiting

5

Catharina Hospital

Eindhoven, Netherlands

Not Yet Recruiting

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Research Team

R

Richard ten Broek

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Cine magnetic resonance imaging vs high-resolution ultrasonography for detection of adhesions after laparoscopic and open incisional hernia repair: a matched pair pilot analysis.

T Mussack, T Fischer, R Ladurner...

https://pubmed.ncbi.nlm.nih.gov/16247569