Consequences and complications of peritoneal adhesions.
H van Goor
https://pubmed.ncbi.nlm.nih.gov/17824967Actively Recruiting
Led by Radboud University Medical Center · Updated on 2025-01-15
100
Participants Needed
5
Research Sites
869 weeks
Total Duration
Researchers are evaluating the accuracy of functional cine magnetic resonance imaging (MRI) in detecting and mapping internal abdominal adhesions. Adhesions commonly form after abdominal surgery as part of healing but can cause complications like chronic pain, bowel obstruction, and difficulties during repeat surgeries. Currently, no validated imaging method exists to reliably map these adhesions before surgery. The study uses a CineMRI scan of the abdomen performed at 1.5 Tesla to identify adhesions. The main goal is to measure how sensitive and specific this imaging technique is at detecting adhesions between the abdominal wall and other tissues. The trial is designed as a prospective multicenter observational study involving patients undergoing reoperation, focusing on both adhesion presence and location. Participants will receive the CineMRI scan, and researchers will compare imaging results to surgical findings to evaluate accuracy. The primary measurement is sensitivity and specificity after 2 weeks. Approximately 100 patients are expected to enroll, with the study completing by December 2019. The trial monitors how well the MRI detects adhesions to the abdominal wall and between organs without additional interventions or treatments.
CONDITIONS
Cine-magnetic Resonance Imaging (MRI) Detecting Intra Abdominal Adhesions
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Total: 5 locations
1
Rijnstate Hospital
Arnhem, Gelderland, Netherlands
Not Yet Recruiting
2
Radboud University Nijmegen Medical Center
Nijmegen, Gelderland, Netherlands
Actively Recruiting
3
Jeroen Bosch Hospital
's-Hertogenbosch, Netherlands
Not Yet Recruiting
4
Gelre Hospital
Apeldoorn, Netherlands
Not Yet Recruiting
5
Catharina Hospital
Eindhoven, Netherlands
Not Yet Recruiting
R
Richard ten Broek
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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H van Goor
https://pubmed.ncbi.nlm.nih.gov/17824967A Lienemann, D Sprenger, H O Steitz...
https://pubmed.ncbi.nlm.nih.gov/11058638T Mussack, T Fischer, R Ladurner...
https://pubmed.ncbi.nlm.nih.gov/16247569