Actively Recruiting

Phase 2
Age: 18Years - 80Years
All Genders
NCT06798402

Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium Stibogluconate

Led by Al-Mustafa University College · Updated on 2025-09-30

80

Participants Needed

1

Research Sites

38 weeks

Total Duration

On this page

Sponsors

A

Al-Mustafa University College

Lead Sponsor

A

Al-Mustansiriyah University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Aim of the trial to evaluate the effectiveness of intralesional ciprofloxacin 0.2% solution as a local injection in treating cutaneous leishmaniasis and compare its effect with intralesional sodium stibogluconate (SSG) 10% intravenous solution in cutaneous leishmaniasis as a local injection. In a randomized parallel groups clinical trial, patients were divided into two groups based on therapeutic regimen: 1) intralesional sodium stibogluconate weekly injection and 2) intralesional ciprofloxacin injection. Each lesion was considered a case in the final analysis. Each lesion will be followed up for 90 days (censor endpoint) or until the lesions are cured.

CONDITIONS

Official Title

Ciprofloxacin Intralesional Injection for the Treatment of Cutaneous Leishmaniasis Compared to Sodium Stibogluconate

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with single or multiple (less than seven lesions) lesions of cutaneous leishmaniasis
Not Eligible

You will not qualify if you...

  • Patients who received anti-leishmaniasis treatment locally or systemically for the last month before this study
  • Patients on prolonged corticosteroid therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mustansiriyah University

Baghdad, Iraq, 10047

Actively Recruiting

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Research Team

H

Hayder Adnan Fawzi, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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