Actively Recruiting
Circadian Rhythm and Other Factors in Memory Clinic Patients
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-02-19
1200
Participants Needed
2
Research Sites
938 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
I
Institut National de la Santé Et de la Recherche Médicale, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
The CIRCAME study is a bicentric study of patients from 2 memory clinics in Paris. The main objective is to identify circadian rhythm components and other individual risk factors (sociodemographic, behavioral, and health related factors) associated with the diagnosis of subtypes (AD, Lewy bodies, vascular, frontotemporal dementia) and stages (cognitively healthy, mild cognitive impairment, clinical dementia) of dementia, independent of known risk factors (sociodemographic and genetic) and assess the relevance of use of these factors in primary care for screen of dementia including subtypes and stages. A secondary objective is to determine factors associated with progression of the disease, in terms of cognitive decline and limitations in activities of daily living, as well as progression to dementia among cognitively healthy controls and patients with mild cognitive impairment, up to 15 years after the inclusion period.
CONDITIONS
Official Title
Circadian Rhythm and Other Factors in Memory Clinic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient of legal age (18 or over)
- Signed informed consent form
- Patient affiliated to the french social security system
You will not qualify if you...
- Skin allergy to plastic
- Diagnosis of psychiatric disorder that can explain all cognitive symptoms
- Inability to come accompanied for patients with a Mini-Mental State Examination (MMSE) cognitive score �38 or a clinician assessment indicating the need to be accompanied (e.g. wheelchair use, agitation)
- Participation at the time of inclusion and during the 9-day period of wearing the accelerometer in interventional research with potential impact on circadian rhythm
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Centre de neurologie Cognitive / CMRR
Paris, France, France, 75010
Actively Recruiting
2
Hôpital de Jour Gériatrique et consultation mémoire
Paris, France, France, 75018
Actively Recruiting
Research Team
C
Claire PAQUET, MDPhD
CONTACT
S
Séverine SABIA, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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