Actively Recruiting

Age: 18Years +
All Genders
ID05480644

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Led by Duke University · Updated on 2025-11-19

300

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are creating a blood sample repository from adults diagnosed with primary or metastatic brain tumors treated at the Duke Cancer Center Radiation Oncology Department. This observational study aims to explore how circulating biomarkers relate to outcomes following radiation therapy in these patients. Participants provide blood samples that will be studied to understand the association between circulating immune cells and treatment effects. The research focuses on collecting samples at specific times, including six weeks after radiation therapy, to measure immune cell levels. During the study, participants undergo blood draws for sample collection, and researchers monitor the number of circulating immune cells in the blood six weeks post-treatment. The study involves no active intervention, and participation duration varies depending on treatment schedules and sample collection timing. The main outcome is the number of circulating immune cells after radiation therapy.

CONDITIONS

Brief Title

Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Sample Collection

Duration - Up to 6 weeks post radiation therapy

Participants provide blood samples to study circulating biomarkers related to radiation therapy outcomes.

1 to 2 visits depending on timing of radiation therapy

Trial Site Locations

Total: 1 location

1

Duke Cancer Center

Durham, North Carolina, United States, 27710

Actively Recruiting

Loading map...

Research Team

K

Kaitlin Bailey, RN OCN

L

Linda Kaltenbach, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

Similar Trials

18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastas...

Brain Metastases

Actively Recruiting

1 location

Isotoxic High Dose (iHD) Fractionated Stereotactic Radiation...

Brain Metastases, Adult

Actively Recruiting

1 location

Hypofractionated Stereotactic Radiotherapy for Treating Brai...

Brain Metastases, Adult

Actively Recruiting

2 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here