Actively Recruiting
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
Led by UConn Health · Updated on 2025-08-12
500
Participants Needed
1
Research Sites
1147 weeks
Total Duration
On this page
Sponsors
U
UConn Health
Lead Sponsor
C
CT Department of Public Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to determine if two proteins in the blood are increased during acute heart failure. These two proteins are produced when the heart becomes dysfunctional and unable to contract normally. They may then be released into the blood and be detected by standard method in the research laboratory. Thus, the purpose of this study is to determine the relation between the change of these two proteins in the blood and the occurrence of acute heart failure. At this time, detection of an increase in these proteins in the blood is not known to be associated with any disease or heart failure.
CONDITIONS
Official Title
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged >18 years
- Stable or decompensated heart failure, regardless of left ventricular ejection fraction
- Clinical symptoms of decompensated heart failure such as shortness of breath, lung crackles, swelling, raised jugular venous pressure, or abdominal fluid
- Imaging evidence of heart failure including enlarged heart, poor heart contraction, or abnormal echocardiographic findings
- Healthy individuals without prior heart attack or heart failure to serve as controls
You will not qualify if you...
- Unable to provide informed consent
- Cardiac or non-cardiac surgery within 3 months before enrollment
- Pregnancy is not an exclusion criterion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030
Actively Recruiting
Research Team
F
Fahad E Shah
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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