Actively Recruiting

Age: 20Years +
All Genders
NCT03635255

Circulating microRNAs and Adverse Cardiovascular Outcomes in Patients With Coronary Artery Disease

Led by National Taiwan University Hospital · Updated on 2025-07-17

460

Participants Needed

1

Research Sites

409 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Coronary artery disease (CAD) resulting from atherosclerotic obstruction of epicardial coronary arteries accounts for more than one-third of deaths in subjects over the age of 35 worldwide. The global incidence of CAD is on the rise owing to the international epidemic of obesity, type 2 diabetes and aging, all of which are potent risk factors for coronary atherosclerosis. Participants with CAD are at high risk for subsequent adverse cardiovascular (CV) events and death; it has been estimated that one out of every five CAD patients will experience at least one adverse CV event during a 5-year follow up period. There is, however, no reliable diagnostic tool to predict the risk of adverse CV events or death in participanrs with CAD. Increasing evidence suggests that miRNAs are stably present in serum, plasma, urine, saliva and other body fluids and are considered a novel class of non-invasive biomarkers for various diseases including cancer, neurodegenerative and cardiovascular diseases

CONDITIONS

Official Title

Circulating microRNAs and Adverse Cardiovascular Outcomes in Patients With Coronary Artery Disease

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female older than 20 years old
  • History of cardiovascular disease, including coronary heart disease or peripheral vascular disease
Not Eligible

You will not qualify if you...

  • Significant valvular or congenital heart disease
  • Cancer
  • Receiving immunosuppressive therapy
  • Other conditions or treatments deemed unsuitable by your physician

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NTUH

Taipei, Taiwan

Actively Recruiting

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Research Team

C

Chau chung Wu, PhD

CONTACT

M

Mei chen Huang, Master

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Circulating microRNAs and Adverse Cardiovascular Outcomes in Patients With Coronary Artery Disease | DecenTrialz