Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
NCT06395246

Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs

Led by Institut Investigacio Sanitaria Pere Virgili · Updated on 2024-10-04

60

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main aim of the present study is to evaluate the effectiveness of two dietary protocols: Daily Caloric Restriction (DCR) and Early Time-Restricted Feeding + DCR (eTRE) on metabolic homeostasis and the influence of circulating extracellular vesicles (EVs) as inter-organ communication elements in obese patients.

CONDITIONS

Official Title

Circulating Microvesicles Regulating Metabolic Homeostasis in Obesity After Caloric Restriction Programs

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 70 years old
  • Body mass index (BMI) between 27 and 40 kg/m2
  • No underlying illnesses except those related to excess weight
  • Signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Serious systemic diseases not related to obesity such as cancer, kidney, or severe liver disease
  • Autoimmune or inflammatory diseases like rheumatoid arthritis and asthma
  • Pregnancy or lactation
  • Vegetarian or irregular diet
  • Severe eating disorders
  • Infection symptoms or signs in the past month
  • Use of chronic anti-inflammatory steroids or nonsteroidal anti-inflammatory drugs
  • Recent antibiotic treatment
  • Uncontrolled alcoholism or drug abuse
  • Rotating or night shift work

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospital Universitario de Tarragona Juan XXIII

Tarragona, Tarragona, Spain, 43005

Actively Recruiting

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Research Team

J

Juan José Vendrell Ortega, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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