Actively Recruiting

Age: 18Years +
MALE
NCT01961713

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Led by Massachusetts General Hospital · Updated on 2025-11-25

200

Participants Needed

1

Research Sites

817 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

P

Prostate Cancer Foundation Clinical Research Consortium

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will evaluate a method to detect tumor cells that are circulating in the blood without getting a biopsy. The investigators already know from other studies that cancer tumors shed a small number of cells into the bloodstream every day. These are called circulating tumor cells (CTCs). Some early studies indicate the amount and type of CTCs in the blood can help determine the status of the tumor itself and the way it is responding to treatment. In this study, the investigators will compare the number of CTCs in the blood at different time frames before and after surgery to remove the prostate.

CONDITIONS

Official Title

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male
  • 18 years of age or older
  • Pathologically confirmed diagnosis of prostate adenocarcinoma
  • Non-metastatic prostate cancer
  • Planned radical prostatectomy at Massachusetts General Hospital
Not Eligible

You will not qualify if you...

  • Prior radiation therapy, hormone therapy, or other medical treatment for prostate cancer before prostatectomy
  • Metastatic prostate cancer
  • Prior or current diagnosis of epithelial malignancy, except for certain skin cancers (squamous cell carcinoma or basal cell carcinoma)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Massachsuetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

R

Richard J Lee, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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