Actively Recruiting

Phase Not Applicable
Age: 18Months - 90Years
All Genders
Healthy Volunteers
NCT07296250

Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT

Led by Chang Gung Memorial Hospital · Updated on 2025-12-22

100

Participants Needed

1

Research Sites

156 weeks

Total Duration

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AI-Summary

What this Trial Is About

The aim 1 of this trial is the development of the Circulating tumor cells (CTCs) definition of oral cancer minimal residual disease (MRD), and aim 2 is a prospective trial of oral cancer treatment. If this trial is successful, it is expected that it may be able to provide a standard diagnostic tool (MRD in Oral Cavity Squamous Cell Carcinoma (OCSCC)) and treatment mode (extended adjuvant chemotherapy with low-dose oral chemotherapy). The survival rate of patients will be improved.

CONDITIONS

Official Title

Circulating Tumor Cell Counts in Postoperative ENE-Positive Oral Cavity Cancer Patients After Adjuvant CCRT

Who Can Participate

Age: 18Months - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 90 years
  • Histologically confirmed diagnosis of head and neck squamous cell carcinoma (HNSCC)
  • Completed surgical treatment and identified as having high-risk factors, followed by concurrent chemoradiotherapy
  • Willing to continue follow-up visits at the hospital after completion of treatment
Not Eligible

You will not qualify if you...

  • Presence of psychiatric disorders
  • Deemed unsuitable for participation by the attending physician
  • Unwilling to participate in the study

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Trial Site Locations

Total: 1 location

1

Linkou Chang Gung Memorial Hospital

Taoyuan City, Taiwan, 333423

Actively Recruiting

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Research Team

C

ChunTa Liao, PhD

CONTACT

C

Chia-Hsun Hsieh, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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