Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04354064

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Led by Washington University School of Medicine · Updated on 2026-02-20

100

Participants Needed

1

Research Sites

396 weeks

Total Duration

On this page

Sponsors

W

Washington University School of Medicine

Lead Sponsor

R

Roche Sequencing Solutions

Collaborating Sponsor

AI-Summary

What this Trial Is About

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular residual disease (MRD) detection timepoint. Ultimately, the integration of ctDNA into the clinical workflow has the potential to enhance cancer diagnosis, treatment, surveillance, and prognosis, and guide clinical decision-making in this era of personalized precision medicine.

CONDITIONS

Official Title

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Eligible healthy donors must be at least 18 years old
Not Eligible

You will not qualify if you...

  • Healthy donors younger than 18 years old

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Washington University School of Medicine

St Louis, Missouri, United States, 63110

Actively Recruiting

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Research Team

M

Melissa Reimers, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors | DecenTrialz