Actively Recruiting
Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors
Led by Indiana University · Updated on 2026-05-04
130
Participants Needed
1
Research Sites
343 weeks
Total Duration
On this page
Sponsors
I
Indiana University
Lead Sponsor
N
Natera, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will evaluate the utility of ctDNA detection in patients with high-risk stage I, stage II, and stage III germ cell tumor disease to develop a tool for post-treatment cancer cell detection.
CONDITIONS
Official Title
Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or older at the time of consent
- Ability to provide written informed consent and HIPAA authorization
- Histologically or serologically confirmed seminomatous or non-seminomatous germ cell tumor, including embryonal carcinoma, choriocarcinoma, yolk sac tumor, or teratoma
- High-risk clinical stage I disease (per investigator discretion), clinical stage II, or clinical stage III or IS disease
- Archival tissue available for germ cell tumor diagnosis
You will not qualify if you...
- Any concurrent disease or condition making participation inappropriate
- Serious medical disorder interfering with safety
- Dementia, altered mental status, or psychiatric condition preventing informed consent
- Currently being tested for minimal residual disease with other experimental platforms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States, 46202
Actively Recruiting
Research Team
K
Kathleen Moore, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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