Actively Recruiting

Age: 18Years +
All Genders
NCT06653062

Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence Surveillance

Led by Tongji Hospital · Updated on 2024-12-30

50

Participants Needed

1

Research Sites

184 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, observational, single-center study. The purpose of this study is to evaluate the efficacy of circulating tumor mitochondrial DNA (ct-mtDNA) in plasma as a biomarker for minimal residual disease (MRD) assessment and recurrence monitoring in patients with hepatocellular carcinoma.

CONDITIONS

Official Title

Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence Surveillance

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with hepatocellular carcinoma (HCC)
  • Diagnosis of HCC according to American or European liver disease guidelines
  • At least one measurable lesion based on RECIST v1.1 or mRESIST criteria
  • Expected survival time of 12 weeks or more
  • Signed informed consent and ability to follow study procedures
Not Eligible

You will not qualify if you...

  • Patients with other active tumors or severe complications
  • Insufficient tumor tissue for MRD detection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tongji Hospital

Wuhan, Hubei, China, 430030

Actively Recruiting

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Research Team

Z

Ze-yang Ding, M.D.

CONTACT

H

Han Gao

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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