Actively Recruiting
Led by University of Alberta · Updated on 2025-08-21
3975
Participants Needed
1
Research Sites
N/A
Total Duration
U
University of Alberta
Lead Sponsor
A
Alberta Innovates Health Solutions
Collaborating Sponsor
Liver cirrhosis causes serious health problems and early death for many patients with digestive diseases. There are gaps in care that lead to high hospital readmission rates and lower quality care. The Cirrhosis Care Alberta (CCAB) program is a three-year quality improvement effort designed to enhance care quality, reduce hospital use, and meet the needs of both patients and healthcare providers across Alberta by addressing multiple factors that contribute to hospital stays and readmissions. The CCAB intervention includes a comprehensive care bundle with admission and discharge order sets focusing on managing cirrhosis complications, frailty, malnutrition, alcohol use disorder, and community transition. It also offers patient and caregiver education to improve self-management and supports provider education for nurses and physicians on cirrhosis care and alcohol use treatments. Additionally, community care pathways target common complications like hepatic encephalopathy and ascites to provide timely support and reduce emergency visits. Participants will be involved throughout the three-year study with assessments of hospital length of stay and readmission rates, emergency and outpatient visits, survival, disease severity, and how well the intervention is implemented. These outcomes will be measured at baseline and over one to two years to evaluate the program's impact. The study uses non-randomized groups including usual care and intervention with or without electronic medical record integration.
CONDITIONS
Cirrhosis Care Alberta (CCAB): A Pragmatic Type II Hybrid Effectiveness Implementation Trial
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 years
Participants receive care guided by a standardized cirrhosis order set aimed at improving management of cirrhosis complications, frailty, malnutrition, alcohol use disorder, and transitions to community care.
Visits occur as part of routine hospital admissions and follow-up care
Duration - Up to 3 years
Participants are observed for outcomes such as hospital readmission, length of stay, emergency department visits, outpatient visits, and survival throughout the study period.
Ongoing monitoring during and after intervention
Total: 1 location
1
University of Alberta
Edmonton, Alberta, Canada, T6G 2S8
Actively Recruiting
P
Puneeta Tandon, MD
M
Michelle Carbonneau, MN, NP
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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Michelle Carbonneau, Ejemai Amaize Eboreime, Ashley Hyde...
https://pubmed.ncbi.nlm.nih.gov/32552833