Actively Recruiting
CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients
Led by University of Wisconsin, Madison · Updated on 2026-04-13
20
Participants Needed
1
Research Sites
404 weeks
Total Duration
On this page
Sponsors
U
University of Wisconsin, Madison
Lead Sponsor
V
Veloxis Pharmaceuticals
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a Phase II/III, Single-center, Prospective, Open-label, Single Arm Study of 20 Simultaneous Kidney Pancreas recipients who received a transplant at least 3 months, but no more than 5 years prior, with a history of tremors following transplantation.
CONDITIONS
Official Title
CIRTEN-Simultaneous Pancreas-Kidney Transplant Recipients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 70 years
- Able to understand and provide consent
- History of Diabetes Type 1 or Insulin-Dependent Diabetes Type 2 with Chronic Kidney Disease
- Received simultaneous pancreas-kidney transplant 3 to 60 months prior
- History of tremors following transplantation
- Stable pancreas allograft function without need for insulin or oral anti-diabetic agents
- Stable kidney allograft function
- Currently taking Immediate-Release tacrolimus
- Women of child-bearing potential must have a negative pregnancy test at entry
You will not qualify if you...
- Currently on extended-release tacrolimus immunosuppressive regimen
- History of tremors before transplantation
- Solitary pancreas transplant recipients
- History of solid organ transplant other than kidney or pancreas
- Uncontrolled infection as determined by investigator
- Presence of Donor Specific Antibodies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Wisconsin
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
J
Jon S Odorico, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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