Actively Recruiting

Age: 18Years +
All Genders
ID07031089

City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area

Led by University Hospital, Grenoble · Updated on 2026-03-02

150

Participants Needed

2

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying liver fibrosis, a condition linked to cirrhosis and liver cancer, which causes many deaths in France. The study focuses on evaluating a care pathway designed to improve early detection and management of liver fibrosis in patients at risk, particularly in primary care settings. This pathway aims to help manage risk factors and ensure appropriate specialist referrals, addressing challenges such as limited awareness and access to Fibroscan40, a non-invasive liver fibrosis test. The care pathway involves screening patients aged 18 and older who have a Fibroscan40 result of 8 kPa or higher, indicating significant liver fibrosis. These tests are requested by primary care practitioners based on screening recommendations using the FIB-4 score. The study does not alter patient care but collects data and conducts telephone interviews to evaluate how well risk factors are managed and if patients are referred to specialists as needed. Participants will undergo their usual care, including Fibroscan40 testing, and researchers will collect information on management of fibrosis risk factors, patient satisfaction, and social factors related to liver fibrosis risk over up to 30 months. The study measures include the frequency of risk factors, specialist consultation rates, and overall adherence to the care pathway. No additional procedures are required beyond routine care and data collection for evaluation.

CONDITIONS

Brief Title

City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Underwent a Fibroscan40 at CHU de Grenoble-Alpes or CPTS-SEG requested by a primary care practitioner
  • Fibroscan40 result of 8 kPa or higher
  • Fibroscan40 performed between January 2023 and January 2026
Not Eligible

You will not qualify if you...

  • Patients who have expressed opposition to participating in the study
  • Patients under guardianship or deprived of liberty
  • Patients with a known chronic liver disease currently being monitored at the time of Fibroscan40

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 30 months

Participants who undergo routine care are observed with data collected from existing clinical practice and telephone interviews to evaluate management of risk factors for liver fibrosis.

Data collection and telephone interviews as per routine care

Trial Site Locations

Total: 2 locations

1

Communauté Professionnelle Territoriale de Santé Sud Est Grenoblois

Grenoble, France

Not Yet Recruiting

2

Grenoble Alpes University Hospital

Grenoble, France

Actively Recruiting

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Research Team

A

Anna Borowik, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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