Actively Recruiting
City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area
Led by University Hospital, Grenoble · Updated on 2026-03-02
150
Participants Needed
2
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying liver fibrosis, a condition linked to cirrhosis and liver cancer, which causes many deaths in France. The study focuses on evaluating a care pathway designed to improve early detection and management of liver fibrosis in patients at risk, particularly in primary care settings. This pathway aims to help manage risk factors and ensure appropriate specialist referrals, addressing challenges such as limited awareness and access to Fibroscan40, a non-invasive liver fibrosis test. The care pathway involves screening patients aged 18 and older who have a Fibroscan40 result of 8 kPa or higher, indicating significant liver fibrosis. These tests are requested by primary care practitioners based on screening recommendations using the FIB-4 score. The study does not alter patient care but collects data and conducts telephone interviews to evaluate how well risk factors are managed and if patients are referred to specialists as needed. Participants will undergo their usual care, including Fibroscan40 testing, and researchers will collect information on management of fibrosis risk factors, patient satisfaction, and social factors related to liver fibrosis risk over up to 30 months. The study measures include the frequency of risk factors, specialist consultation rates, and overall adherence to the care pathway. No additional procedures are required beyond routine care and data collection for evaluation.
CONDITIONS
Brief Title
City-Hospital Collaboration for Early Detection of Liver Fibrosis in Primary Care: A Secondary Prevention Project in the Grenoble Health Area
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Underwent a Fibroscan40 at CHU de Grenoble-Alpes or CPTS-SEG requested by a primary care practitioner
- Fibroscan40 result of 8 kPa or higher
- Fibroscan40 performed between January 2023 and January 2026
You will not qualify if you...
- Patients who have expressed opposition to participating in the study
- Patients under guardianship or deprived of liberty
- Patients with a known chronic liver disease currently being monitored at the time of Fibroscan40
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 30 months
Participants who undergo routine care are observed with data collected from existing clinical practice and telephone interviews to evaluate management of risk factors for liver fibrosis.
Data collection and telephone interviews as per routine care
Trial Site Locations
Total: 2 locations
1
Communauté Professionnelle Territoriale de Santé Sud Est Grenoblois
Grenoble, France
Not Yet Recruiting
2
Grenoble Alpes University Hospital
Grenoble, France
Actively Recruiting
Research Team
A
Anna Borowik, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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