Actively Recruiting
Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-03-30
40
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
A
Alcon Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
Retrospective, comparative, interventional, randomized, single-center study, contralateral (the patient's 2 eyes will be implanted: 1 CPO and the other APO) Patients presenting for cataract surgery with a request for presbyopia correction and managed as part of routine clinical practice. The main aim of the study is to demonstrate that contrast sensitivity is better with the Clareon PanOptix (CPO) intraocular lens (IOL) compared with the AcrySof PanOptix (APO) IOL 3 months after implantation.
CONDITIONS
Official Title
Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older
- Patients presenting for cataract surgery in routine clinical practice and eligible for multifocal IOL implantation (toric and non-toric)
- Patients with grade 2 or 3 cataract density and comparable visual acuity in both eyes
- Negative pregnancy test if applicable
- Signed consent to participate in the study
- Patient affiliated to a social security scheme or entitled beneficiary
You will not qualify if you...
- Children under 18 years of age
- Pregnancy or breastfeeding in progress or planned during the study
- History of anterior or posterior segment eye pathology including retinal vascular occlusive disease, retinal detachment, peripheral retinal laser photocoagulation, AMD, or glaucoma
- Any inflammation of the anterior or posterior eye segment or history of diseases causing intraocular inflammation
- Clinically significant corneal pathology affecting visual results
- Moderate or severe dry eye that could affect study measurements
- History of intraocular or corneal surgery (refractive or trauma-related)
- Presence or history of amblyopia or monofixation syndrome
- Conditions increasing risk of zonular disruption during surgery affecting IOL centration or orientation
- Planned additional eye surgeries including limbal relaxing incision, astigmatic keratotomy, or laser refractive surgery
- Irregular astigmatism identified by corneal topography
- Patients under guardianship, curatorship, or safeguard of justice
- Patient under AME
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Assistance Publique - Hôpitaux de Paris, Ophtalomopôle - Hôpital COCHIN
Paris, Île-de-France Region, France, 75014
Actively Recruiting
Research Team
D
Dominique MONNET, MD, PhD
CONTACT
V
Valérie PLENCE, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here