Study of Spasticity Patterns in Upper and Lower Limbs and Their Effect on Quality of Life in Adults With Multiple Sclerosis

What this Trial Is About

Multiple sclerosis MS is a chronic neurological disease that often involves spasticity, leading to difficulties in movement and lower quality of life. This study aims to classify spasticity patterns in the upper and lower limbs of adults with MS and to explore how these patterns relate to their quality of life. The study is designed as a prospective cross-sectional observational research to better understand these spasticity patterns and their impact on patients daily function. Adult patients with MS and clinical spasticity will participate in a single study visit where spasticity will be assessed using the Modified Ashworth Scale and limb posture evaluations. Functional performance will be measured with the Timed 25-Foot Walk Test for lower limbs and the 9-Hole Peg Test for upper limbs. The study will also evaluate the impact of spasticity on quality of life using the Patient-Reported Impact of Spasticity Measure PRISM. During the visit, demographic and clinical data will be collected, including disease duration, subtype, and previous treatments. Researchers will record spasticity severity and patterns in different joints of the upper and lower extremities. Functional ability and disability levels will be assessed, and participants will complete questionnaires about how spasticity affects their daily life and psychosocial well-being. The results aim to provide detailed descriptions of spasticity in MS to improve individualized rehabilitation and treatment planning.

Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple Sclerosis