Actively Recruiting
Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic Infection
Led by University Hospital, Strasbourg, France · Updated on 2026-01-13
260
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Clindamycin is an antibiotic with several advantages: high oral bioavailability and good bone and joint penetration. In France, it is a recommended drug for other types of Streptococcus spp. osteoarticular infections and can be used as an alternative to amoxicillin for periprosthetic infections, including when implants are retained. The hypothesis of this study is that clindamycin is no less effective than other drugs commonly used to treat periprosthetic Streptococcus spp. infections. The primary objective of this study is to evaluate the success rate of Streptococcus spp. periprosthetic joint infections treated with clindamycin compared to other antibiotic treatments.
CONDITIONS
Official Title
Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient (aged 18 years or older) at the time of surgery for infection
- Probable or proven periprosthetic infection with Streptococcus spp. according to EBJIS diagnostic criteria
- Patient operated on in one of the associated centers between 2013 and 2024
You will not qualify if you...
- Patient who underwent joint resection or amputation
- Patient who was treated with suppressive antibiotic therapy lasting more than 6 months decided upon prior to surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de Chirurgie Orthopédique Septique - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
S
Stéphane KLEIN, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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