Actively Recruiting
Clinical Application Research of Scleral Lenses in Ocular Surface Diseases
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2024-08-15
20
Participants Needed
1
Research Sites
107 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the therapeutic efficacy of scleral lenses in patients with irregular corneal astigmatism stemming from ocular surface diseases (OSD), focusing on visual acuity improvement, comfort, and overall satisfaction. This prospective clinical study enrolled patients diagnosed with OSD-related irregular corneal astigmatism. Participants underwent comprehensive ophthalmic evaluation, including corneal topography, visual acuity assessment, and tear film analysis. Qualified subjects were fitted with scleral lenses and followed up at intervals of one week, one month, and three months post-fitting. The primary outcomes measured were uncorrected and corrected visual acuity, comfort levels assessed via a standardized questionnaire, and fitting success rates. Data were analyzed using appropriate statistical methods to compare pre- and post-intervention values.
CONDITIONS
Official Title
Clinical Application Research of Scleral Lenses in Ocular Surface Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with irregular corneal astigmatism, including post-keratoconus cross-linking surgery, post-keratoplasty, and trauma-induced corneal irregularities
- Volunteers willing to participate, sign informed consent, and comply with treatment and follow-up
- Individuals aged 18 years or older, any gender
- Cases collected between January 2023 and August 2024
You will not qualify if you...
- Unable or unwilling to sign consent or follow study procedures
- Nursing or pregnant women
- Individuals with acute ocular inflammation or infection
- Corneal endothelial cell density less than 1000/mm6
- Those required to wear lenses overnight
- Poor compliance with study requirements
- Not meeting hygiene standards for lens wear
- Other reasons deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Second Affiliated Hospital of Zhejiang University Hospital
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
M
ming xiu jin
CONTACT
R
rui yi zhu
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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