Study of Advanced Eye Imaging and Effects of Ocufolin on Eye Health in Adults

What this Trial Is About

Researchers are evaluating the clinical use of advanced eye imaging tools such as optical coherence tomography OCT, retinal function imager RFI, slit-lamp biomicroscopy SLB, and pattern electroretinogram PERG in both diseased eyes and healthy controls. The study includes people with various eye-related conditions including multiple sclerosis, dry eye syndromes, diabetic retinopathy, presbyopia, myopia, and dementia. The study aims to better understand eye conditions through detailed imaging and functional assessments. The study has two phases. The first phase is observational, where participants undergo imaging and eye examinations without treatment. The second phase is interventional, where participants take an over-the-counter medical food called Ocufolin daily for six months with a gradually increasing dose. Participants in the interventional phase take one capsule each morning for one week, two capsules each morning for the second week, and three capsules each morning for the remaining four and a half months. Participants will be followed and assessed for up to two years. Eye structure and function will be measured using OCT, optical coherence tomography angiography OCTA, functional slit-lamp biomicroscopy FSLB, and retinal function imager RFI. Measurements include retinal microstructure, retinal and conjunctival blood flow, corneal thickness, and tear film thickness. The study includes regular imaging and visual acuity testing, with the goal of understanding changes in eye health and vascular function over time.

Clinical Applications of Advanced Ophthalmic Imaging