Actively Recruiting

FEMALE
NCT06527807

Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium

Led by Beijing Tiantan Hospital · Updated on 2024-08-07

1200

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

Sponsors

B

Beijing Tiantan Hospital

Lead Sponsor

A

Affiliated Hospital of Jiangnan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objectives of this study are: (1) to describe the detailed clinical characteristics and prognosis of ASPP patients in order to explore the risk factors of ASPP, and to compare the short-term and long-term functional recovery outcomes between them and their controls; (2) to evaluate the risk of recurrent stroke, particularly during subsequent pregnancies, in ASPP patients; (3) to assess the short-term and long-term outcomes of their offsprings and their future development status. This study is divided into three parts. The first part is a case-control study to explore the risk factors of ASPP and the predictors of the prognosis of ASPP patients. The second part is a cohort study to evaluate the impact of ASPP on the risk of recurrent stroke. The third part is a cohort study to assess the impact of ASPP on the short-term and long-term outcomes of their offsprings by comparing the offsprings of ASPP patients with the offsprings of non-ASPP participants.

CONDITIONS

Official Title

Clinical Characteristics and Prognosis of Acute Stroke in Pregnancy and Puerperium

Who Can Participate

FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients 18 years of age or older
  • Patients or their representatives agree to personal information collection and provide oral or online informed consent
  • Patients must be pregnant or within 6 weeks postpartum (for offspring outcome study)
Not Eligible

You will not qualify if you...

  • Patients or their representatives refuse follow-up
  • Missing critical baseline demographic, clinical, or neuroimaging data
  • Offsprings with congenital malformation or inborn errors of metabolism
  • Complications affecting cerebral blood flow, such as amniotic fluid embolism during pregnancy
  • Family history of severe mental illness in relatives other than parents or siblings of offsprings
  • Acute myocardial infarction during pregnancy
  • Non-spontaneous stroke events caused by surgery or other causes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Tiantan hospital

Beijing, Beijing Municipality, China, 100070

Actively Recruiting

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Research Team

Z

Zihan Yin, MD

CONTACT

Z

Zhongji Zhang, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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