Actively Recruiting

Age: 18Years - 60Years
All Genders
NCT06285734

Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals with Abdominal Distention

Led by Shandong University · Updated on 2024-12-12

402

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

Sponsors

S

Shandong University

Lead Sponsor

Q

Qilu Hospital of Shandong University (Qingdao)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Abdominal distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis. This symptomatology is frequently observed in various conditions, including small intestinal bacterial overgrowth (SIBO) and abnormal orocecal transit time (OCTT). The utilization of the breath test as a non-invasive diagnostic approach has become widespread in recent years for identifying SIBO and abnormalities in OCTT. In this study, the prevalence of SIBO and OCTT irregularities in individuals presenting with abdominal distention was ascertained through the implementation of the breath test. Furthermore, the correlation between abdominal distention and SIBO/OCTT was analysed to enhance the elucidation of the underlying etiology of abdominal distention. These findings aim to offer valuable insights for refining clinical comprehension and strategies related to the diagnosis and treatment of abdominal distention.

CONDITIONS

Official Title

Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals with Abdominal Distention

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 to 70 years
  • Patients with abdominal bloating and/or abdominal distension as their main complaint
  • Patients with abdominal distension more prominent than other symptoms
Not Eligible

You will not qualify if you...

  • Pregnant or lactating patients
  • History of gastrointestinal cancer or gastrointestinal surgery
  • Patients with food intolerance or diagnosed or suspected lactose intolerance
  • Patients with diseases of the urinary, immune, nervous, mental, or other non-digestive systems
  • Patients who used antibiotics, probiotics, or had endoscopic exams within two weeks
  • Patients who used motility enhancers, secretory enhancers, antifoaming agents, spasmolytics, opioids, or antidepressants within the past week
  • Patients unwilling or unable to give informed consent

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Gastroenterology Department of Qilu Hospital

Jinan, Shandong, China, 250012

Actively Recruiting

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Research Team

X

Xiuli Zuo, MD,PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals with Abdominal Distention | DecenTrialz