Comparing Albumin Platelet Rich-Fibrin and Platelet-rich Fibrin to Gelatin Sponge for Healing After Free Gingival Graft Surgery

What this Trial Is About

Researchers are comparing two types of platelet-rich fibrin materialsAlbumin Platelet Rich-Fibrin Alb-PRF and Platelet-rich fibrin PRFto a gelatin sponge to see how they affect recovery after free gingival graft harvesting from the palate. This randomized controlled trial involves adult patients undergoing this dental procedure to assess postoperative pain and healing outcomes. Participants will be randomly assigned to one of three groups Alb-PRF, PRF, or a control group using a gelatin sponge. Each participant will have 10 ml of blood drawn to prepare the Alb-PRF or PRF membranes, which will be applied to the donor site and secured with sutures. The control group will receive a gelatin sponge at the donor site. All surgeries are done under sterile conditions with local anesthesia, followed by a standardized postoperative care including ibuprofen, mouthwash, dietary advice, and oral hygiene instructions. Participants will be followed for 28 days with visits on days 3, 7, 14, 21, and 28 after surgery. Pain levels will be recorded using a Visual Analog Scale VAS at specified intervals. Researchers will also monitor wound healing, tissue color match, re-epithelialization, and clinical wound area. Sutures will be removed after 7 days and patients will be advised on pain management and oral care while reporting any unusual symptoms for early intervention.

Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting