Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment

What this Trial Is About

Functional dyspepsia (FD) is a common long-lasting digestive disorder affecting many people. Researchers are studying the course of FD in patients receiving medication-based treatments, such as proton pump inhibitors, tricyclic antidepressants, and prokinetics. This observational study aims to understand how symptoms improve or persist over time and to explore clinical and psychological factors, like anxiety and sleep problems, that may influence treatment outcomes. The study is sponsored by Air Force Military Medical University, China. Participants with FD who meet specific criteria will be observed without receiving experimental treatment. Assessments include symptom scores, dyspepsia subtypes, anxiety and depression scales, quality of life questionnaires, and symptom diaries. The main measure is improvement in symptoms at six months, with follow-up assessments up to twelve months. There is no experimental intervention; instead, researchers track patients' responses to their usual medication-based care. During the study, participants will complete questionnaires and symptom diaries at various points, including one day, one month, three months, six months, and twelve months after their initial visit. Researchers will analyze these data to understand symptom changes and factors related to improvement or persistence of FD symptoms. Participants will be monitored for six months primarily, with some measures extending to one year, to assess their condition and quality of life while receiving standard medical care.

Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment