Actively Recruiting
Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment
Led by Air Force Military Medical University, China · Updated on 2025-04-16
300
Participants Needed
4
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Functional dyspepsia (FD) is one of most common chronic gastrointestinal disorders. Several types of drugs were demonstrated to be effective in reduction or remission of symptoms and severity of FD, including proton pump inhibitors (PPI), Tricyclic antidepressant and prokinetics. However, the clinical course of FD after taking medication-based treatment was unknown. Furthermore, 20-50% patients remained persistent or worsening of dyspepsia symptoms after treatment. Previous studies have suggested psychological factors (eg. anxiety, sleep disturbance) were related to less improvement of symptoms in natural clinical course. However, there is limited evidence in terms of clinical and psychological factors for less improvement in patients receiving medication treatment for dyspepsia.
CONDITIONS
Official Title
Clinical Course of Functional Dyspepsia and Factors Predicting Outcome in Patients Receiving Medication-based Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Patients who meet Rome IV criteria for functional dyspepsia
- Normal upper endoscopy and abdominal ultrasonography within the past year
You will not qualify if you...
- Presence of local or systemic diseases causing dyspeptic symptoms, including active peptic ulcer, cholecystitis, gallstone, gastrointestinal obstruction, gastroparesis, liver or kidney injury, hematological, endocrine, metabolic diseases, malignancy, cardiovascular or cerebrovascular diseases
- Organ failure as defined by Marshall standard
- Severe psychiatric illnesses
- Known malignancy
- Pregnancy or lactation
- Unable to provide consent
- Suspected or identified bowel obstruction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Lanzhou University Second Hospital
Lanzhou, Gansu, China
Not Yet Recruiting
2
The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710032
Not Yet Recruiting
3
Xijing 986 Hospita
Xi'an, Shaanxi, China, 710032
Not Yet Recruiting
4
Xijing Hospital of Digestive Diseases
Xi'an, Shaanxi, China, 710032
Actively Recruiting
Research Team
Y
Yanglin Pan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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